Tauopathies and Synucleinopathies: Molecular Mechanisms of Neurodegeneration

Neurodegenerative diseases are often characterized by abnormal protein aggregation. This session will focus on how tau (in Alzheimer’s, frontotemporal dementia) and alpha-synuclein (in Parkinson’s, Lewy body dementia) misfold and spread in the brain, leading to neurodegeneration. Experts will present findings on prion-like propagation mechanisms, genetic risk factors, and novel drug targets aimed at stopping protein aggregation. The session will also highlight therapeutic strategies such as monoclonal antibodies and small-molecule inhibitors designed to disrupt these toxic protein interactions. This session is ideal for molecular biologists, neuroscientists, and drug developers.

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